Clinical Guidelines

Position Statements

Introduction
The Australian Haemophilia Centre Directors' Organisation (AHCDO) is the national medical body for haemophilia in Australia.
The International Society on Thrombosis and Haemostasis (ISTH), European Association for Haemophilia and Allied Disorders (EAHAD) and World Federation of Hemophilia (WFH) issued a statement on 6 May 2025 for a call to action for the importance of a continued commitment to innovation and access in haemophilia care.
AHCDO Members are Directors of Australian Haemophilia Treatment Centres (HTCs) and have been involved in gene therapy clinical trials over the past 10 years.
AHCDO has been leading the implementation of gene therapy in Australia through the Gene and Emerging Therapies Subcommittee and the collaborative development of the Gene Therapy Roadmap.
AHCDO is actively developing of resources for streamlining national implementation using Standard Operating Procedures and nationally consistent training.
AHCDO is also working closely with Haemophilia Foundation Australia (HFA) to implement resources related to Gene Therapy.
Position Statement
The Australian Haemophilia Centre Directors’ Organisation strongly supports the Statement and encourages the continued advancement of gene therapy and other innovative haemophilia treatments.
AHCDO will continue to
• contribute to research and clinical developments in innovative therapies, including gene therapies and non-replacement therapies;
• strengthen global collaboration, research and education;
Feedback
Feedback on the Position Statement can be directed to AHCDO at info@ahcdo.org.au.
Position Statement approved by AHCDO Executive Committee
30 May 2025
Download Position Statement
Introduction
The Australian Haemophilia Centre Directors' Organisation (AHCDO) is the national medical body for haemophilia in Australia.
The International Society on Thrombosis and Haemostasis (ISTH), an international professional medical scientific organization dedicated to advancing the understanding, prevention, diagnosis, and treatment of conditions related to thrombosis and haemostasis, has published the first clinical practice guideline utilizing strict GRADE methodology for the treatment of congenital haemophilia A and B.
The Guidelines are a set of 13 recommendations, addressing aspects of haemophilia A and B care. They are accompanied by extensive remarks providing additional context and guidance for interpretation and implementation.
The international response to the Guidelines has been varied and there have been significant concerns raised.
Following the review of the Guidelines and subsequent articles reviewing the Guidelines, AHCDO has developed the following position on the ISTH Guidelines.
Position Statement
The Australian Haemophilia Centre Directors’ Organisation, confirm that AHCDO adopts the World Federation of Haemophilia Guidelines for the Management of Hemophilia, 3rd edition in full with amendments/ additions for the Australian context.
AHCDO is not supportive of adopting the ISTH Guidelines, in the current form, in Australia.
Feedback
Feedback on the Position Statement can be directed to AHCDO at info@ahcdo.org.au.
Position Statement approved by AHCDO Executive Committee
30 May 2025
Download Position Statement
The Australian Haemophilia Centre Directors’ Organisation, in consultation with the National Blood Authority, adopts the World Federation of Haemophilia Guidelines for the Management of Hemophilia, 3rd edition in full with the amendments / additions for the Australian context.
Download WFH Guidelines for the Management of Hemophilia, 3rd edition
Download Position Statement (October 2024)
The Position Statement above should be read in conjunction with The framework for the management of bleeding disorders in Australia (The Framework); National Blood Authority; 2025 - link to The Framework
Previous Guidelines
RESCINDED Guidelines AHCDO and National Blood Authority; Version 1; 2016
Download RESCINDED Guidelines
If you have any questions or feedback, please direct your comments to info@ahcdo.org.au